Non-Hazardous but Potent
While not classified as a severe acute toxin, it is a potent pharmaceutical agent requiring careful handling to prevent inhalation of dust or accidental ingestion.
Eyes: Flush with water for 15 minutes and seek medical advice
Skin: Wash thoroughly with soap and water
Leucovorin Calcium, also known as folinic acid calcium salt, is a vital pharmaceutical ingredient that acts as a reduced form of folic acid. Unlike folic acid, it does not require the enzyme dihydrofolate reductase for activation, making it highly effective in clinical settings where metabolic pathways are inhibited.
In the Indian pharmaceutical landscape, this chemical is primarily sourced by oncology drug manufacturers and large-scale formulation units. It is essential for 'leucovorin rescue' therapy, which mitigates the toxic side effects of methotrexate in patients undergoing treatment for various cancers, including osteosarcoma and leukemia.
For procurement in India, buyers should prioritize suppliers with GMP (Good Manufacturing Practice) certification and comprehensive COA (Certificate of Analysis) documentation. Given its sensitivity to light and moisture, ensuring cold-chain logistics and vacuum-sealed packaging is critical for maintaining potency during transit across domestic regions.
Leucovorin Calcium pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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Leucovorin Calcium prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
No, it is a reduced form of folic acid that bypasses the need for enzymatic activation, making it more effective in specific clinical scenarios.
It is primarily used as a 'rescue' agent in methotrexate-based chemotherapy for cancer patients.
Yes, it is recommended to store it in a cool, dry place, ideally between 2°C and 8°C to maintain maximum stability.
Yes, all reputable Indian suppliers provide a Certificate of Analysis (COA) detailing purity, heavy metals, and related substances.
Yes, Leucovorin Calcium is sensitive to light and should be stored in amber containers or opaque packaging.
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