N-(3-Chloro-4-Fluorophenyl)
CAS: 162012-67-1Safety Information
Hazardous Substance
May cause skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate laboratory safety gear.
Eyes: Flush with water for 15 minutes and seek medical attention.
Skin: Wash thoroughly with soap and water; remove contaminated clothing.
AboutN-(3-Chloro-4-Fluorophenyl)
This compound, identified by CAS 162012-67-1, is a specialized quinazoline derivative. It serves as a critical impurity standard and synthetic intermediate, particularly in the development and manufacturing of Afatinib, a potent tyrosine kinase inhibitor used in cancer therapy.
In the Indian pharmaceutical landscape, this chemical is essential for R&D laboratories and API manufacturers focusing on high-end oncology drugs. It enables local manufacturers to conduct rigorous impurity profiling and process validation, ensuring compliance with international pharmacopeial standards for exported drug products.
When sourcing this chemical in India, buyers should prioritize suppliers who provide comprehensive Certificates of Analysis (CoA) and NMR/HPLC data. Due to its sensitivity and specialized nature, procurement should be handled through authorized distributors who maintain cold-chain or controlled-temperature logistics to preserve chemical integrity.
Applications & Industries
Price in IndiaN-(3-Chloro-4-Fluorophenyl)
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin--4-Amine pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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Frequently Asked Questions
What is the price of N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin--4-Amine in India?
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin--4-Amine prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
Is this chemical used for commercial API production?
Yes, it is primarily used as a synthetic intermediate for the production of Afatinib and related quinazoline-based APIs.
Does it come with a Certificate of Analysis?
Yes, all professional suppliers in India provide a CoA including HPLC purity and structural identification data.
Is this product in stock in India?
Most specialized chemical distributors in hubs like Hyderabad, Mumbai, and Ahmedabad maintain stock for R&D quantities.
What is the primary storage requirement?
It should be stored in a cool, dry, and dark environment, ideally at 2-8°C to prevent degradation.
Can it be used for clinical trials?
Yes, provided the grade meets the specific regulatory requirements and quality standards for the intended clinical phase.
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