Irritant
Causes skin irritation, serious eye irritation, and may cause respiratory irritation.
Eyes: Rinse cautiously with water for several minutes; seek medical attention.
Skin: Wash with plenty of soap and water; remove contaminated clothing.
4-Chloropicolinic Acid Methyl Ester Hydrochloride (CAS 176977-85-8) is a specialized pyridine derivative widely recognized in the pharmaceutical industry as a key intermediate. It is specifically utilized in the synthesis of Sorafenib, a potent multikinase inhibitor used in the treatment of various cancers. Its chemical structure allows for precise substitution reactions, making it invaluable for medicinal chemistry research and large-scale API manufacturing.
In the Indian market, this compound is primarily sourced by pharmaceutical manufacturers and contract research organizations (CROs) located in major hubs like Hyderabad, Ahmedabad, and Mumbai. As the Indian pharmaceutical sector continues to expand its focus on complex generic and oncology drug production, the demand for high-purity intermediates like this hydrochloride salt has seen consistent growth.
When procuring this chemical, buyers should prioritize suppliers who provide comprehensive COA (Certificate of Analysis) documentation, including HPLC purity profiles and impurity data. Given its sensitivity to moisture and light, it is essential to ensure that the material is stored in controlled environments and shipped in robust, moisture-resistant packaging to maintain its chemical integrity throughout the supply chain.
4-Chloropicolinic Acid Methyl Ester Hydrochloride pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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4-Chloropicolinic Acid Methyl Ester Hydrochloride prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
Yes, provided the supplier offers the necessary documentation and quality certifications required for your specific regulatory filing.
It is primarily used as a key intermediate in the synthesis of the API Sorafenib.
While stable at room temperature, it is recommended to store it in a cool, dry place; long-term storage is best at 2-8°C.
Most reputable Indian suppliers provide small-scale samples for quality validation and method development.
Yes, it is stocked by major chemical distributors in pharmaceutical hubs like Hyderabad and Ahmedabad.
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