Irritant
Causes skin irritation, serious eye irritation, and may cause respiratory irritation.
Eyes: Rinse cautiously with water for 15 minutes, seek medical attention.
Skin: Wash with plenty of soap and water; remove contaminated clothing.
5-Bromonicotinic Acid Ethyl Ester (CAS 20986-40-7) is a functionalized pyridine derivative characterized by the presence of a bromine atom and an ethyl ester group. This structural configuration makes it an essential scaffold for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, which are fundamental in modern drug synthesis.
In the Indian chemical landscape, this compound is primarily sourced by pharmaceutical manufacturers and contract research organizations (CROs) located in hubs like Hyderabad, Ahmedabad, and Mumbai. It is highly valued for its role in the development of nicotinic receptor ligands and various kinase inhibitors, supporting the robust growth of India's generic and innovative drug manufacturing sectors.
When procuring this chemical in India, buyers should prioritize suppliers who provide comprehensive Certificates of Analysis (CoA) and batch-specific impurity profiles. Given its sensitivity to moisture and light, ensuring that the material is stored in controlled environments is essential for maintaining the integrity of the ester functionality during transit and long-term storage.
5-Bromonicotinic Acid Ethyl Ester pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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5-Bromonicotinic Acid Ethyl Ester prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
It is primarily used as a synthetic intermediate in the pharmaceutical industry for building complex heterocyclic drug molecules.
While stable, it is recommended to store it in a cool, dry place, ideally away from direct light to prevent degradation.
Yes, the bromine atom at the 5-position makes it an excellent substrate for palladium-catalyzed cross-coupling reactions.
Standard commercial purity is 98%, with 99% available for specialized research applications.
Standard laboratory PPE including gloves, safety goggles, and a lab coat should be worn to avoid skin and eye contact.
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