(E)
CAS: 212776-19-7Safety Information
Irritant and Reactive Compound
Causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate PPE in a well-ventilated area.
Eyes: Rinse cautiously with water for several minutes; seek medical attention.
Skin: Wash with plenty of soap and water; remove contaminated clothing.
About(E)
(E)-Methyl 4-(dimethylamino) But-2-Enoate, also known as Neratinib Impurity 38, is a specialized organic ester characterized by its dimethylamino and crotonate functional groups. In the Indian pharmaceutical landscape, it is highly valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting tyrosine kinase inhibition.
The chemical is primarily utilized by R&D centers and contract manufacturing organizations (CMOs) across India's pharmaceutical hubs like Hyderabad, Ahmedabad, and Mumbai. Its high reactivity makes it an essential component for fine chemical synthesis, requiring precise handling to maintain its structural integrity during the manufacturing process.
When procuring this chemical, buyers should ensure the supplier provides a comprehensive Certificate of Analysis (CoA) including HPLC purity and impurity profiles. Given its sensitivity, it is recommended to source from manufacturers who adhere to stringent quality management systems and offer secure, temperature-controlled logistics to prevent degradation.
Applications & Industries
Price in India(E)
(E)-Methyl 4-(dimethylamino) But-2-Enoate pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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Frequently Asked Questions
What is the price of (E)-Methyl 4-(dimethylamino) But-2-Enoate in India?
(E)-Methyl 4-(dimethylamino) But-2-Enoate prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
What is the primary use of this chemical?
It is primarily used as a key intermediate in the synthesis of the anti-cancer drug Neratinib.
Is this chemical stable at room temperature?
It is recommended to store it in a cool environment, preferably refrigerated, to ensure long-term stability.
Do you provide a Certificate of Analysis?
Yes, all shipments include a CoA detailing purity, moisture content, and impurity profile.
Can this be used for large-scale API manufacturing?
Yes, we supply this in bulk quantities suitable for commercial API production.
What is the typical lead time for delivery in India?
Lead times vary based on stock availability, typically ranging from 1 to 3 weeks for domestic orders.
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