Irritant and Potential Explosive
May cause skin and eye irritation. Potentially explosive if dry; handle with extreme caution and avoid friction or heat.
Eyes: Flush with water for 15 minutes and seek medical attention.
Skin: Wash thoroughly with soap and water; remove contaminated clothing.
6CL-HOBT (6-Chloro-1-hydroxybenzotriazol) is a specialized chemical derivative of benzotriazole. In the pharmaceutical industry, it serves as a vital reagent for facilitating amide bond formation, particularly in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
Within the Indian pharmaceutical landscape, this compound is highly sought after by R&D laboratories and contract manufacturing organizations (CMOs) involved in the production of generic oncology medications. Its role as 'Impurity G' for Cabozantinib makes it a mandatory component for quality control and regulatory compliance testing in Indian pharma export units.
Procurement of 6CL-HOBT requires careful attention to purity levels and batch consistency. Buyers should prioritize suppliers providing comprehensive COAs (Certificates of Analysis) and HPLC data. Given its sensitivity to environmental conditions, sourcing from reputable manufacturers with cold-chain or climate-controlled storage capabilities is recommended for long-term stability.
6CL-HOBT pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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6CL-HOBT prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
No, 6CL-HOBT is a chlorinated derivative of HOBt, specifically used for different reactivity profiles and as a distinct impurity marker.
It is primarily used as a reference standard for Cabozantinib impurity testing and as a coupling reagent in peptide synthesis.
Yes, it is sensitive to heat and friction; it should be handled as a potentially explosive material in its dry state.
Standard orders include a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and HPLC chromatograms.
It is recommended to store it in a cool, dry place, preferably below 25°C, away from direct light.
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