Irritant and Potential Toxicant
This substance may cause skin irritation, serious eye irritation, and respiratory tract irritation. Handle with appropriate personal protective equipment in a controlled environment.
Eyes: Flush with water for 15 minutes and seek medical attention.
Skin: Wash thoroughly with soap and water; remove contaminated clothing.
Methyl 4-Amino-2,3-Difluoro-5-Nitrobenzoate (CAS 284030-58-6) is a specialized organic intermediate characterized by its unique fluorinated nitro-benzoate structure. It is widely recognized in the global pharmaceutical industry as a key impurity and synthetic precursor for MEK inhibitors.
In the Indian market, this chemical is primarily sourced by contract research organizations (CROs) and active pharmaceutical ingredient (API) manufacturers located in hubs like Hyderabad, Ahmedabad, and Mumbai. Its demand is driven by the growing domestic focus on oncology drug development and the production of complex generic APIs for export.
When procuring this material, buyers should prioritize suppliers who provide comprehensive COA (Certificate of Analysis) documentation, including HPLC purity profiles and NMR data. Given its sensitivity to light and moisture, it is essential to verify that the supplier maintains cold-chain or climate-controlled storage conditions during transit.
Methyl 4-Amino-2,3-Difluoro-5-Nitrobenzoate pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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Methyl 4-Amino-2,3-Difluoro-5-Nitrobenzoate prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
It is primarily used as a key intermediate in the synthesis of the anti-cancer drug Binimetinib.
Yes, it is available through specialized chemical distributors and manufacturers, typically in 25kg drum quantities.
Always request a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and HPLC chromatogram.
Yes, it should be handled as a hazardous chemical with standard laboratory PPE, avoiding dust inhalation and skin contact.
Quality is typically verified through HPLC (High-Performance Liquid Chromatography) to ensure purity levels meet the required specifications.
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