Irritant
Causes skin irritation, serious eye irritation, and may cause respiratory irritation.
Eyes: Rinse cautiously with water for 15 minutes; seek medical attention.
Skin: Wash with plenty of soap and water; remove contaminated clothing.
2-Bromo-Isonicotinamide (CAS 29840-73-1) is a functionalized pyridine derivative characterized by its bromine substituent at the 2-position and a carboxamide group at the 4-position. This specific substitution pattern makes it an invaluable intermediate for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, which are essential for constructing complex molecular architectures in drug development.
In the Indian chemical landscape, this compound is primarily sourced by pharmaceutical manufacturers and contract research organizations (CROs) located in hubs like Hyderabad, Ahmedabad, and Mumbai. It is highly valued for its role in the synthesis of kinase inhibitors and other targeted therapeutic agents, supporting India's growing position as a global supplier of high-quality pharmaceutical intermediates.
When procuring this chemical, buyers should prioritize suppliers who provide comprehensive Certificates of Analysis (CoA) and batch-specific impurity profiles. Given its sensitivity to moisture and light, it is recommended to source from vendors offering secure, airtight packaging and reliable cold-chain logistics to ensure the material maintains its structural integrity during transit across India.
2-Bromo-Isonicotinamide pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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2-Bromo-Isonicotinamide prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
It is primarily used as an intermediate in the synthesis of pharmaceutical drugs, particularly for creating pyridine-based active ingredients.
Yes, it is stable under standard shipping conditions, but it should be protected from extreme heat and moisture.
Standard industrial grades are typically 97% pure, while high-grade pharma intermediates are 99% pure.
It should be handled with standard lab safety equipment, including gloves and goggles, to avoid skin and eye contact.
Yes, the bromine atom at the 2-position makes it an excellent substrate for palladium-catalyzed cross-coupling reactions.
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