Flammable and Irritant
This substance is flammable and causes skin and eye irritation. Handle with appropriate personal protective equipment in a well-ventilated area.
Eyes: Rinse cautiously with water for several minutes; seek medical attention.
Skin: Wash with plenty of soap and water; remove contaminated clothing.
2-Bromo-5-Fluorotoluene (CAS 452-63-1) is a specialized organic intermediate characterized by its unique substitution pattern on the toluene ring. Its chemical structure makes it an essential precursor for the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic moieties to enhance metabolic stability and biological activity.
In the Indian chemical market, this compound is primarily sourced by pharmaceutical manufacturers and contract research organizations (CROs) located in key hubs like Hyderabad, Ahmedabad, and Mumbai. It is frequently utilized in the synthesis of DPP-4 inhibitors, including Trelagliptin, where it acts as a vital intermediate for impurity profiling and process development.
When procuring this chemical in India, buyers should prioritize suppliers who provide comprehensive COA (Certificate of Analysis) documentation and GC-purity verification. Given its sensitivity to light and air, procurement should focus on vendors offering high-quality, moisture-proof packaging and reliable cold-chain logistics to ensure product integrity during transit.
2-Bromo-5-Fluorotoluene pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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2-Bromo-5-Fluorotoluene prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
It is primarily used as a synthetic intermediate for APIs, specifically in the production of Trelagliptin and related pharmaceutical compounds.
Yes, it is classified as a hazardous chemical; ensure compliance with local Indian transport regulations for flammable liquids.
Most Indian specialty chemical suppliers provide small-scale samples (100g-500g) for validation before bulk procurement.
The standard market purity is 98%, with 99%+ available for specialized pharmaceutical applications.
While stable at room temperature, it is recommended to store in a cool, dry place away from direct light to prevent degradation.
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