Highly Flammable and Corrosive
Reacts violently with water to release hydrogen chloride gas. Causes severe skin burns and eye damage.
Eyes: Rinse cautiously with water for 15 minutes and seek immediate medical attention.
Skin: Remove contaminated clothing and rinse skin with plenty of water.
Trimethylsilyl Chloride, commonly referred to as TMSCl, is a colorless, volatile liquid with a pungent odor. It serves as a cornerstone reagent in organic synthesis, particularly for the introduction of the trimethylsilyl group into organic molecules. Its high reactivity with nucleophiles makes it an indispensable tool for chemists working on complex molecular structures.
In the Indian industrial landscape, TMSCl is primarily utilized by the pharmaceutical sector for the synthesis of APIs and as a critical reagent in the production of specialty silicones. It is also increasingly sought after by manufacturers of high-performance polymers and surface-modified fillers, where it helps in achieving specific chemical resistance and hydrophobic properties.
Procurement of TMSCl in India requires careful attention to moisture-sensitive handling protocols. Buyers should source from suppliers who provide high-purity, anhydrous grades in sealed, inert-gas-blanketed packaging. Given its hazardous nature, it is recommended to verify the supplier's compliance with safety regulations and their capability for secure, specialized logistics.
Trimethylsilyl Chloride pricing in India depends on grade, order quantity, and delivery location, and it moves with market conditions — so a single fixed price is rarely accurate for a specific requirement.
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Trimethylsilyl Chloride prices in India vary by grade, order quantity and delivery location, and move with market conditions. To get the current price for your requirement, submit an enquiry on Chemical Dekho and receive verified quotes from suppliers and manufacturers within 24 hours.
Yes, it reacts violently with water and moisture to produce HCl gas.
It is used as a protecting group for hydroxyl and amino groups during complex API synthesis.
It must be stored in a cool, dry place under an inert gas blanket to prevent hydrolysis.
Yes, it is readily available through major chemical distributors and specialty chemical manufacturers in India.
Chemical-resistant gloves, safety goggles, and a face shield are mandatory, along with working in a fume hood.
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