What is acetonitrile?
Acetonitrile, also called methyl cyanide or cyanomethane, is a clear polar solvent widely used in HPLC, analytical chemistry, pharmaceutical manufacturing, extraction, and synthesis workflows. It is valued for low viscosity, miscibility with water, and strong performance in analytical solvent systems.
Acetonitrile buying can be grade-sensitive. Industrial users may compare purity and water content, while HPLC and pharma users require tighter specifications, UV absorbance controls, residue limits, and stronger batch documentation.
Chemical Dekho links acetonitrile to CAS 75-05-8 so procurement teams can compare supplier offers by correct chemical identity, grade, specification, packaging, and documentation.
CAS Number
75-05-8
Common names
Methyl cyanide, cyanomethane
Buyer focus
Grade precision
Applications
Where acetonitrile is used
Acetonitrile is used where a polar solvent with analytical or synthesis utility is required.
HPLC and analytical chemistry
Used as a mobile phase solvent and analytical reagent where UV profile, purity, and water content matter.
Pharmaceutical synthesis
Used in process chemistry, purification, and specialty pharma workflows requiring documented solvent quality.
Extraction and purification
Used in extraction, cleanup, crystallization support, and purification workflows in labs and production.
Specialty chemical manufacturing
Used as a solvent or intermediate support in selected specialty chemical processes.
Grade Selection
How to choose the right acetonitrile grade
Buyers should distinguish industrial, pharma, laboratory, and HPLC grades. HPLC-grade acetonitrile requires stronger purity, UV, residue, acidity/alkalinity, and water controls than general industrial use.
A good acetonitrile RFQ should mention application, grade, water limit, UV or analytical requirement, packaging, delivery location, and COA/SDS expectations.
RFQ checklist
- Industrial, pharma or HPLC grade
- Water content
- UV/analytical requirement
- Residue limits
- Packaging size
- COA/SDS/TDS
Specification Snapshot
Acetonitrile specifications buyers usually compare
Acetonitrile should be compared by grade and analytical specification. HPLC-grade and industrial-grade offers are not interchangeable.
Safety basics: acetonitrile is flammable and toxic.
This blog is a buyer guide, not a replacement for your SDS, site EHS procedure, or local compliance requirements.
Acetonitrile should be handled with ventilation, compatible PPE, ignition-source control, and SDS-based procedures. Teams should avoid inhalation, ingestion, and skin exposure.
Connect to Acetonitrile page
Ready to compare acetonitrile suppliers?
If you are sourcing acetonitrile in India, open the Acetonitrile CAS 75-05-8 page to compare grade, specifications, documentation, packaging, and suppliers.
Better RFQs start here
Use the product page to align product identity, specifications, documentation, and supplier comparison before you ask for quotes.
FAQ
Acetonitrile buying questions
What is acetonitrile used for?
Acetonitrile is used in HPLC, analytical chemistry, pharmaceutical synthesis, extraction, purification, and specialty chemical manufacturing.
What is HPLC grade acetonitrile?
HPLC grade acetonitrile has tighter purity, UV absorbance, residue, and water specifications for analytical chromatography workflows.
Is acetonitrile hazardous?
Yes. Acetonitrile is flammable and toxic, so users should follow SDS guidance, use ventilation, and wear suitable PPE.
Where can I compare acetonitrile suppliers in India?
Chemical Dekho provides an Acetonitrile CAS 75-05-8 page for specification-led supplier discovery.
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Read guideTurn acetonitrile research into a supplier shortlist.
Chemical Dekho connects chemical discovery with actual procurement intent, so buyers can search by CAS, compare specs, and speak with suppliers using the right technical vocabulary.